Uniqueness of Our Technology

The groundbreaking technology of Inzipio offers a fully digital process chain for patient-specific preoperative surgical planning. What sets it apart is its seamless integration of individual imaging data and advanced convolutional neural networks, offering a streamlined journey starting with the processing of individual imaging data with the aid of convolutional neural networks through patient-specific surgical planning to the automated design of surgical cutting guides that can be 3D printed and used in the operating room to transfer the digital planning to the patient. The first application of this technology targets reconstructive facial surgery with bony transplants, but thanks to the software’s modular structure applications in other related indications and surgical domains are relatively easy to achieve. The key functionalities are specifically tailored to translate medical requirements to technical implementations and thus allow for the direct transfer of the knowledge of surgical experts to each unique patient case making real patient-specific surgical planning an achievable reality.

Inzipio presents a sophisticated, fully digital process chain for patient-specific preoperative surgical planning, designed to meet the exacting standards of surgeons worldwide.

Key Technological Advancements:

1. Automatic segmentation of patient-individual imaging data
2. Streamlined workflow from data processing to surgical planning
3. Automated design of 3D-printable surgical cutting guides
4. Modular software architecture for multi-domain applications

Clinical Applications:

The initial focus is on reconstructive facial surgery utilizing bony transplants. However, the modular structure of the software facilitates expansion into related surgical specialties.

Distinctive Features:

• Precise translation of medical requirements into technical implementations
• Direct application of surgical expertise to individual patient cases
• Realization of truly patient-specific surgical planning

For surgeons and medical experts, Inzipio offers a powerful tool to enhance preoperative planning accuracy and potentially improve surgical outcomes. The technology's ability to integrate individual patient data with advanced algorithms represents a significant step forward in personalized surgical approaches. Inzipio presents an opportunity in the growing field of precision medicine and surgical technology. Inzipio stands at the intersection of advanced imaging technology, artificial intelligence, and surgical expertise, offering a robust solution for the complex challenges of modern surgical planning.

I. Facial Reconstruction After Tumor Removal

This is our initial and pilot application, but our technology has a wide range of applications. Facial reconstructions after tumor removal will be our initial target with our first product release in mid-2025. This will be the concept demonstrator for validation of our approach. Step by step we will add applications to our web platform, such as Jaw Augmentations, Osteotomies in Extremities and Orthognathic Surgeries.

Image Segmentation

Medical image segmentation is the process of transferring volumetric data (e.g. from computed tomography or magnetic resonance imaging) to a geometric representation of surfaces of anatomical structures that can be used for subsequent operation planning. Especially the processing of imaging data of the bones of the facial region is challenging, as typically a large amount of artifacts, caused by metal inlays is spoiling the imaging data and thus makes manual segmentation cumbersome and time consuming.

Inzipio’s solution is the use of artificial intelligence in its implementation as convolutional neural networks to allow for an automated and reproducible extraction of the indiviudal bone geometries even in challenging sets of data.

Process Chain of digital surgical planning